City of Hope researchers ID how most common breast cancer becomes resistant to treatment

(City of Hope) City of Hope has identified how cancer cells in patients with early-stage breast cancer change and become resistant to hormone or combination therapies. Andrea Bild, Ph.D., used single-cell RNA sequencing to identify resistant traits cancer cells acquire; these cancer cells can persist despite therapy. The team also identified when these resistant traits are acquired and found them as early as two weeks after the start of a treatment regimen -- months faster than current methods.